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TNM is a staging system used to codify prostate cancer into grades and stages so accurate decisions can be made in regards to treatments and also prognosis. All types of cancer have similar grading systems with individual tweaks for the particular cancer being staged. http://www.upmccancercenters.com/cancer/prostate/TNMsystem.html Clark's level is another grading system that helps grade the level of tumor invasion into the surrounding tissue. Clark's level is more commonly used with melanoma. With prostate cancer Clark's level could be used to indicate whether the cancer was confined to the prostate gland or had spread. http://www.medterms.com/script/main/art.asp?articlekey=19818
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