Friday, January 4, 2008

Is prostate cancer an endocrine system disorder

Is prostate cancer an endocrine system disorder?
Can it be considered for an endocrine system disorder or disease.
Cancer - 2 Answers
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1 :
No it is part of the male reproductive system. The endocrine system are glands that produce hormones. It includes the pituitary, thyroid, adrenals, pancreas, ovaries and testis.
2 :
Hi Sam, There is rising evidence both from epidemiology studies and animal models that precise endocrine-disrupting compounds might regulate the expansion or development of prostate cancer. In huge part, these things come into view to be connected to intervention with estrogen signaling, either through interacting with ERs or by regulating steroid metabolism and altering estrogen levels within the body. In humans, epidemiologic confirmation associates specific pesticides, PCBs and lifeless arsenic exposures to eminent prostate cancer risk. Studies in animal models also show intensification of prostate carcinogenesis with several other environmental estrogenic compounds including cadmium, UV filters and BPA. Significantly, there seems to be sharp sensitivity of the prostate to these endocrine disruptors throughout the critical developmental windows together with utero and neonatal time points as well as during puberty. For more information on endocrine system disorder, Visit